4-Chloro-Pyrimidine-5-Carboxylic Acid Ethyl Ester - Names and Identifiers
4-Chloro-Pyrimidine-5-Carboxylic Acid Ethyl Ester - Physico-chemical Properties
Molecular Formula | C7H7ClN2O2
|
Molar Mass | 186.6 |
Density | 1.311±0.06 g/cm3(Predicted) |
Boling Point | 278.2±20.0 °C(Predicted) |
Flash Point | 122.05°C |
Vapor Presure | 0.004mmHg at 25°C |
pKa | -1.62±0.16(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.527 |
4-Chloro-Pyrimidine-5-Carboxylic Acid Ethyl Ester - Introduction
Ethyl is an organic compound with the chemical formula C7H6ClNO2. The following is an introduction to its nature, use, preparation and safety information:
Nature:
1. Appearance: ethyl is a white crystalline solid.
2. melting point: about 80-82 degrees Celsius.
3. Solubility: It is soluble in some organic solvents, such as ethanol, dimethylformamide and chloroform.
Use:
1. Ethyl l is a commonly used organic synthesis intermediate that can be used to synthesize a variety of organic compounds.
2. It can be used to prepare active molecules in the field of pesticides and medicines.
3. In the pharmaceutical industry, it can be used to synthesize antibacterial drugs and other active compounds.
Preparation Method:
There are many synthesis methods for ethyl l, and the following is one of the commonly used methods:
First, 4-chloropyrimidine is reacted with potassium hydroxide under an alkaline condition to form a potassium salt. The potassium salt is then reacted with ethanol in the presence of acetic anhydride to produce 4-chloropyrimidine-5-acid. Finally, 4-chloropyrimidine-5-acid was reacted with thionyl chloride to prepare ethyl.
Safety Information:
1. ethyl l should avoid contact with skin and eyes. Wear appropriate protective equipment when in use.
2. It should be stored in a dry, cool place, away from fire and oxidant.
3. in use and storage, should comply with the relevant safety procedures.
please note that this is only a basic introduction to ethyl l, and the specific nature, use, preparation and safety information need to be carefully studied and practiced according to the actual situation.
Last Update:2024-04-09 21:01:54